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53F METABOLIC SYNDROME



 

This is an online Elog book to discuss our patient deidentified health data shared after taking his/ her guardians sign informed consent

Here we discuss our individual patient problems through series of inputs from available Global online community of experts with n aim to solve those patient clinical problem with collect current best evidence based input

This Elog also reflects my patient centered online learning portfolio.

I have been given this case to solve in an attempt to understand the topic of " Patient clinical data analysis" to develop my competancy in reading and comprehending clinical data including history, clinical finding, investigations and come up with a diagnosis and treatment plan

Thankyou Dr Stimita for helping in History

53 year old female housewife by occupation resident of coochbihar admitted with complains of generalised weakness since 6 years


The patient's medical history reveals that she was asymptomatic until six years ago when she presented with weight loss, xerostomia, and anorexia. She sought medical attention at a local medical facility, where she was diagnosed with Diabetes mellitus and subsequently initiated on oral hypoglycemic agents.

Around four years ago, the patient began experiencing generalized asthenia and easy fatigability, leading to the diagnosis of both Hypertension and hypothyroidism.

Approximately four years ago, the patient complained of cervical discomfort, prompting a diagnostic consideration of cervical spondylosis. This condition was managed with a course of physiotherapy.

Currently, the patient reports intermittent occurrences of generalized asthenia, easy fatigability, and xerostomia. She also experiences sporadic episodes of lumbosacral discomfort and bilateral coxalgia, which intensify during prolonged periods of sitting.

Furthermore, the patient describes sporadic episodes of burning epigastric discomfort, which is alleviated by food ingestion or resolves spontaneously after a certain period. She occasionally experiences early morning nausea that subsides after breakfast.

Sleep disturbances are also reported, with frequent nocturnal awakenings disrupting the patient's sleep pattern.

Lastly, the patient presents with sporadic bilateral lower limb paresthesias, without specific exacerbating or relieving factors.

PSYCHOSOCIAL HISTORY

Raised in a rural environment as part of a nuclear family, she pursued her education up to the 10th grade. However, societal norms prevalent in her village led her to discontinue her studies thereafter.

Subsequently, she immersed herself in domestic duties. At 26, she married a businessman. Following their union, she conceived naturally and gave birth to a son within the first year. Opting to concentrate fully on her young child, she elected to terminate her pregnancy a year later.

Around 6 to 7 years later, she conceived once again, only to experience a miscarriage. This incident weighed on her for months, yet the support of her family aided in her recovery.

Currently, she enjoys a harmonious nuclear family life with her husband, son, and daughter-in-law. Her son actively participates in their hardware store business, while her daughter-in-law works as a school teacher.

Initially, she managed household duties independently. However, in recent years, she has faced increasing fatigue and weakness. With her daughter-in-law's teaching commitments, she sought the help of a maid for household tasks.

Her daily routine involves waking up at 6:30 am, engaging in chores, enjoying tea with biscuits, preparing meals, and spending quality time with family. Due to her diabetes diagnosis, she shifted from consuming rice for dinner to eating chapati.

Despite her talkative and proactive nature, she's been battling fatigue for 4-5 years, which has left her dissatisfied. Health issues in her husband and daughter-in-law, alongside her own medical regimen, have become a concern despite financial stability.

She experiences heightened anxiety over minor matters and constantly worries about her health. Her sleep patterns are erratic, with occasional full-night sleep but often interrupted rest.


PAST HISTORY

Known case of Diabetes since 6 years
Initially on tab glycomet 500mg now changed to tab vildgliptin and metformin 50/500mg po/Od

Known case of Hypertension since 4 years
On tab telmasartan 40mg but doesn’t take it regularly 

Known case of Hypothyroidism 
Initially on T Thyroxine 25mcg for 2 years and increased to 50mcg
Now on T thyroxine 32.5mcg

Had cataract surgery to right eye

PERSONAL HISTORY

no smoking/alcohol history
Consumes Areca nut/ pan two per day

General examination

Height : 5’4
Body weight: 67kgs
Mid arm circumference: 25cms
Abdominal circumference: 90cms

BP : 130/80mmhg
PR : 75bpm
GRBS : 
Temp: afebrile

No pallor, icterus,cyanosis, clubbing, lymphadenopathy, edema

SYSTEMIC EXAMINATION

Cardiovascular system:
S1 and S2 heard no murmurs heard 

Central nervous system: 
No focal neurological deficit, cranial nerve intact

Respiratory system:Bilateral air entry-present ,Normal vesicular breath sounds-heard

Abdominal examination: soft and non tender, No Hepatomegaly, spleen is not palpable.



Clinical images









PROVISIONAL DIAGNOSIS 

Metabolic syndrome with known case of DM,HTN and Hypothyroidism 

INVESTIGATIONS


USG ABDOMEN

GRADE 2 fatty liver


HEMOGRAM

HB - 10.9gm/dl
TLC- 8000 cells/cumm
N/L/E/B- 57/34/7/0
PCV - 33.4 vol%
MCV- 91.0 fl 
MCH- 29.7 pg
MCHC- 32.6 %
RDW-CV - 14.1%
RDW-SD - 47.8 fl
RBC- 3.67 millions/cumm
PLATELETS- 2.5lakhs/cumm

CUR
COLOUR- pale yellow
Appearance- clear
Reaction- acidic
SP gravity- 1.010
ALBUMIN- NIL
SUGAR- NIL
BILE SALTS- NIL
BILE PUGMENTS- NIL
PUS CELLS - 2-4
EPITHELIAL CELLS- 2-3
RBC - NIL
CRYSTALS- NIL
CASTS- NIL
AMORPHOUS DEPOSITS - NIL

THYROID PROFILE

T3 - 1.25 ng/ml
T4 - 11.68 micro g/dl
TSH - 7.35 micro iu/ml

FBS 135mg/dl
PPBS
HBA1C

LIPID PROFILE
Total cholesterol - 211mg/dl
Triglycerides- 106mg/dl
HDL- 43.1mg/dl
LDL-113 mg/dl
VLDL-21.2mg/dl

RFT
UREA - 31mg/dl
CREATININE- 0.8mg/dl
URIC ACID-5.7mg/dl
CALCIUM- 10.0mg/dl
PHOSPHORUS-3.1mg/dl
SODIUM- 144meq/L
POTASSIUM - 4.4 mEq/L
CHLORIDE- 99 mEq/L

DVL referal in view of allergic contact dermatitis 



Opthalomology referal in view of DOV





OMFS Referal in view of tooth extraction 



ENT Referal in view of ear pain 






DIAGNOSIS

METABOLIC SYNDROME 
ALLERGIC CONTACT DERMATITIS 
IMMATURE SENILE CATARACT IN BOTH EYES
OTITIS EXTERNA in right ear

Treatment 

Adviced cataract surgery by Opthal dept 

Mupirocin ointment for application in external ear - adviced by ENT for otitis externa


Treatment adviced by DVL for allergic contact dermatitis 
Tab Teczine po/Od for one week
Momate F cream for local application for one week
Venusa max lotion for local application for two weeks



Lifestyle modifications 
Physical activity 30mins everyday

Tab vildagliptin and metformin 50/500mg po/Od
Tab telmasartan 40mg po/Od
Tab thyroxine 32.5mcg po/od


Follow up in PaJR
After going home 



Case 8

### Thematic Analysis of the Case

#### 1. **Coding:**
   - **Chronic Conditions:** Diabetes mellitus (6 years), hypertension (4 years), hypothyroidism (4 years), metabolic syndrome, cervical spondylosis.
   - **Musculoskeletal Issues:** Bilateral coxalgia, cervical discomfort, lumbosacral pain.
   - **Psychosocial Stress:** Anxiety about health, family responsibilities, disrupted sleep.
   - **Lifestyle Factors:** Areca nut consumption, household work limitations due to fatigue.

#### 2. **Categorization:**
   - **Metabolic Dysregulation:** Diabetes, hypertension, and hypothyroidism suggest poor metabolic control leading to metabolic syndrome.
   - **Musculoskeletal Pain:** Chronic cervical and lumbar discomfort due to age-related degeneration.
   - **Psychosocial Impact:** Health-related anxiety and the burden of managing family duties.

#### 3. **Theme Identification:**
   - **Multisystem Degeneration in Middle Age:** This case illustrates how metabolic disorders combined with musculoskeletal and mental health issues affect middle-aged women.
   - **Need for Lifestyle Adjustments:** Her management plan highlights the importance of physical activity and consistent medication adherence.
   - **Mental Health Strain on Chronic Disease Management:** Anxiety about health further complicates her condition management and requires addressing alongside physical symptoms.

#### 4. **Theme Representation (Learning Points):**
   - **Interdisciplinary Approach to Metabolic Syndrome:** The patient requires coordinated care to address diabetes, hypertension, and hypothyroidism while managing lifestyle modifications and mental health. 
   - **Impact of Family Dynamics on Health:** The psychosocial context (family responsibilities, health anxieties) influences her health behaviors and condition management, warranting psychological support.

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